ISTH-BAT is dedicated to the collection, curation, analysis, and dissemination of data about bleeding phenotypes. It is backed by a Bleeding History Ontology (BHO), which encodes information about all bleeding symptoms in an electronic format that facilitates standardization and analysis. You are encouraged to review the ontology, which was developed by the Rockefeller University Bleeding History Phenotyping Team (http://bioportal.bioontology.org/ontologies/BHO).
The ISTH-BATR system has: A web-based data collection instrument termed a phenotyping recording instrument that allows the investigator to administer a bleeding history questionnaire from any computer with Internet access. A web-based instrument for recording laboratory results pertaining to hemostasis, PRI Labs. A web-accessible database designated as a data repository (RUBHPSR and ISTH-BATR) that can be queried using our data representation and query utilities.
The project page is https://bh.rockefeller.edu/ISTH-BATR/. ISTH-BATR source code is accessible through bitbucket.
- Elbatarny M, Mollah S, Grabell J, Bae S, Deforest M, Tuttle A, Hopman W, Clark DS, Mauer AC, Bowman M, Riddel J, Christopherson PA, Montgomery RR; Zimmerman Program Investigators, Rand ML, Coller B, James PD. Normal range of bleeding scores for the ISTH-BAT: adult and pediatric data from the merging project. Haemophilia. 2014 Nov;20(6):831-5. doi: 10.1111/hae.12503. Epub 2014 Sep 6. PubMed PMID: 25196510; PubMed Central PMCID: PMC4251588.
- Mollah SA, James PB, Grabell J, Barbour EM, Coller B. Diagnostic Prediction of Von Willebrand Disease using Multiple Bleeding Phenomics Datasets. AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:184. eCollection 2013. PubMed PMID: 24303262.
- Mauer AC, Barbour EM, Khazanov NA, Levenkova N, Mollah SA, Coller BS. Creating an ontology-based human phenotyping system: The Rockefeller University bleeding history experience. Clin Transl Sci. 2009 Oct;2(5):382-5. doi: 10.1111/j.1752-8062.2009.00147.x. PubMed PMID: 20443924.